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RETINAL DEGENERATION
excerpt from
THIS IS WHAT THE DATA SAY ABOUT MONOSODIUM GLUTAMATE TOXICITY and the CENTRAL NERVOUS SYSTEM
(http://www.truthinlabeling.org/Proof_BrainLesions_CNS.html)

Compiled by Adrienne Samuels, Ph.D., May, 2009

Excitotoxins are toxic agents capable of exciting and then poisoning cells or tissues.  Two manufactured excitotoxic amino acids are presently used in quantity in processed foods. Glutamic acid (glutamate) is the most prevalent of the excitotoxic amino acids. Glutamate that has been produced through bacterial fermentation or has been freed from protein through a manufacturing process or through fermentation (we call it MSG) will be found in ingredients including, but not limited to, hydrolyzed protein products, autolyzed yeast, calcium caseinate, sodium caseinate, textured vegetable protein, gelatin, ultra-pasteurized products, and monosodium glutamate.  It is this manufactured glutamate (MSG) that has been administered or fed to subjects in studies where the glutamate produces retinal degeneration, brain lesions, endocrine disorders, and/or adverse reactions. Glutamate found in intact protein has never been shown to cause retinal degeneration, brain lesions, endocrine disorders, or adverse reactions.

Retinal degeneration

In 1957, Lucas and Newhouse(26) first noticed that severe retinal lesions could be produced in suckling mice (and to some extent in adult mice) by a single injection of glutamate. Studies confirming their findings using neonatal rodents (49-52) and adult rabbits(53) followed shortly, with others being reported from time to time (54-58). These studies concerned themselves not only with the confirmation of monosodium glutamate induced retinal lesions, but with the formulation and testing of hypotheses to explain the phenomenon.  

In 2002, Ohguro et al.(27) found that rats fed 10 grams of sodium glutamate (97.5% sodium glutamate and 2.5% sodium ribonucleotide) added to a 100 gram daily diet for as little as 3 months had a significant increase in amount of glutamic acid in vitreous, had damage to the retina, and had deficits in retinal function.

Ohguro et al. also documented the cumulative effect of damage caused by daily ingestion of MSG.

Other reports of toxic effects of monosodium glutamate have come from studies at the University of Pecs, Hungary, where the neuroprotective effects of PACAP in the retina are being studied(28,29).

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IF MSG ISN'T HARMFUL, WHY IS IT HIDDEN?